FBW7

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1.

Scientists had found that FBW7 was missing or altered in certain types of cancer , including leukemia , breast cancer and colon cancer .

科学家发现，一些癌症，比如白血病、乳腺癌和直肠癌，FBW7 基因可能会缺失或发生改变。

2.

In contrast , the FBW7-deficient cells were resistant to a different family of cancer-fighting drugs called BCL2 inhibitors .

与此相反，FBW7 基因缺陷的细胞则会对另一类 BCL2 抑制剂的抗癌药物产生耐药。