Nature9y
HSP90 inhibition leads to degradation of the TYK2 kinase and apoptotic cell death in T-cell acute lymphoblastic leukemia
This two-pronged assault on the mitochondrial apoptotic machinery identifies HSP90 inhibitors as promising drugs for targeting the TYK2-mediated prosurvival signaling axis in T-ALL cells.
Nanoparticle technology demonstrates selective destruction of leukemia cancer cells
Jointly led by Professors Sebyung Kang, Eunhee Kim, and Sung Ho Park from the Department of Biological Sciences at UNIST, the ...
Phys.org1mon
Physical signals as fate deciders: How mechanical forces extrude cells from tissues
Epithelia are dynamic and must constantly deal with cell renewal. Therefore, the removal of cells from a tissue, called apoptotic extrusion, occurs regularly. Its balance is key for epithelia ...