Apoptotic DNA degradation has been thought to be a cell-autonomous process. Recent evidence suggests that heterophagic recognition and engulfment of dying cells by non-apoptotic cells may be ...
This two-pronged assault on the mitochondrial apoptotic machinery identifies HSP90 inhibitors as promising drugs for targeting the TYK2-mediated prosurvival signaling axis in T-ALL cells.
4 个月
AZoLifeSciences on MSNA Novel Mechanism for Apoptotic Cell Removal in Epithelial TissuesNeighboring cells rapidly unite to push these injured and dying (apoptotic) cells out of the way and close any openings that ...
Epithelia are dynamic and must constantly deal with cell renewal. Therefore, the removal of cells from a tissue, called apoptotic extrusion, occurs regularly. Its balance is key for epithelia ...
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