Due to the influence of environmental factors, organisms with identical genotypes, such as identical twins, ultimately express nonidentical phenotypes because each organism encounters unique ...

The first and foremost prerequisite for successful linkage mapping is a set of families in which both the disease phenotype is segregating and the assessment of the phenotypes has been made with ...

Monoallelic loss of PTEN and ARID1A is identified in normal colonic epithelium. The resulting haploinsufficient phenotypes ...

Researchers find that certain antioxidant enzymes, called selenoproteins, significantly contribute to fighting cell aging. The team used a gene knockout mouse model to help them study the effects of ...

More information: Xiaojing Jia et al, Exploring age and gender disparities in cardiometabolic phenotypes and lipidomic ...

The odds of developing systemic lupus erythematosus or systemic sclerosis appear to significantly increase with the use of ...

We begin with a review of the univariate ACE model, and then extend this to two phenotypes as a Cholesky model, introducing the concept of genetic correlation along the way.

Phenotyping children with asthma based on rhinoconjunctivitis symptoms shows that rhinoconjunctivitis may not always be allergy driven.

The findings link psychiatric illnesses, digital phenotypes and genotypes and show how wearable sensors can provide a deeper understanding of psychiatric diseases. Smartwatches that can collect ...