The proteasome-part of the internal cellular machinery-breaks down specific cellular proteins. Ubiquitin is a protein that attaches to other proteins to earmark them for degradation by helping the ...

Protein folding: Ensured by molecular chaperones to maintain functionality. ・Degradation: Damaged proteins are broken down via the ubiquitin-proteasome system or lysosomes. ・Aggregate ...

Her work will provide major insights into the fundamental regulatory mechanisms for the proteasome and controlled protein degradation.

Nobel Laureate Aaron Ciechanover emphasizes the importance of democracy in science for progress and innovation.

C-terminal amidation is a PTM that involves the addition of an amid group to the C-terminus of a peptide or protein. Currently there is no direct evidence to suggest that C-terminal amidation of ...

Booster Therapeutics has announced its inception, backed by a $15m investment, to develop a new class of proteasome activator ...