Antibiotics and Other Sulfonamides to Avoid If You Have a Sulfa Allergy Sulfa drugs are synthetic (man-made) medications made from sulfanilamide that contain antibacterial properties. Sulfa drugs ...

One of the first U.S. trials of a sulfa drug was made in 1936 on a sinus infection of Franklin D. Roosevelt Jr. (he was cured). Since then interest in sulfa cures has centered around other ...