Background: Our primary purpose was to determine the normal range and variability of blood volume (BV) in healthy children, in order to provide reference values during childhood and adolescence.

Athos, Anthony, and John J. Gabarro. "Understanding Another Person, Part I: The Individual Frame of Reference." Harvard Business School Background Note 473-009, August 1972. (Revised September 1976.) ...

This is also applicable to the need for a reference frame to compare values in pathological conditions. These same ethical considerations are less applicable to nephrotic children in remission ...