Up to 20,000 babies may have been affected by exposure to valproate since it was introduced. Some, like the government’s patient safety commissioner, Dr Henrietta Hughes, have branded this “a scandal ...

Ministers have been urged to give financial compensation to women affected by the mesh scandal as the Patient Safety ...

The ACP guideline, published in Annals of Internal Medicine, includes three recommendations centered around monotherapy: ...

The government has been urged to give financial compensation to women affected by the mesh scandal - as the patient safety ...

Sodium valproate—an important drug used to treat epilepsy and bipolar disorder—has a long and controversial history due to safety concerns, particularly for pregnant women, as it can lead to ...

Babies exposed to valproate in the womb are at high risk of serious complications. NICE guidance has been updated to align with the advice provided on the use of valproate by the Medicines and ...

Lithium carbonate and valproate sodium are each recommended as monotherapy for preventing relapses in patients with bipolar disorder and are sometimes used in combination. However, combination ...

Valproic acid dissociates to the valproate ion in the GI tract. The mechanisms by which valproate exerts its therapeutic effects have not been established. It has been suggested that its activity ...

Valproic acid (as sodium salt) 250mg/5mL; oral soln. Valproic acid dissociates to the valproate ion in the GI tract. The mechanisms by which valproate exerts its therapeutic effects have not been ...

Objective: To determine the efficacy and tolerability of magnesium valproate as monotherapy in patients with partial or generalised epilepsy. Design and Setting: This was a nonblinded study ...