COX-2 = cyclooxygenase-2; TCC = transitional cell carcinoma; SqCC = squamous cell carcinoma *Significant increase in number of positive cases compared with control group at P < .05 † Significant ...

Cholangiocarcinoma is a rare but highly malignant primary hepatobiliary cancer with a high rate of mortality. Early diagnosis is difficult and current therapies are ineffective for the advanced ...

Among these, cyclooxygenase (COX) inhibitors, particularly selective COX-2 inhibitors, have gained significant attention due to their ability to reduce inflammation while minimizing ...