AA 是一种罕见的胃肠道癌症，发病率低，每 10 万人中约有 1.3 人发病，且属于罕见病范畴，目前尚无 FDA 批准的特效疗法。标准治疗方案为细胞减灭术联合腹腔热灌注化疗（CRS + HIPEC），但并非所有患者都适合手术。传统观念认为 AA 对全身化疗反应不佳，不过近年来，靶向治疗、免疫治疗和腹腔内定向治疗展现出一定潜力。

Adults with primary primary appendiceal adenocarcinoma face a higher risk of developing a second primary cancer, including colorectal and prostate cancers.

Rate of gene fusion/rearrangement identification in GI cancers as sequencing evolved from limited panels to whole exome sequencing. This is an ASCO Meeting Abstract from the 2025 ASCO Gastrointestinal ...

Comparison of screening outcomes associated with advanced precancerous lesion versus colorectal cancer sensitivity for a blood-based test: A simulation study. This is an ASCO Meeting Abstract from the ...