Abstract Autophagy is a crucial quality control mechanism that degrades damaged cellular components through lysosomal fusion with autophagosomes ...

A recent study from Tata Institute of Fundamental Research, Mumbai, India has revealed new details about how our cells clean up and recycle waste.

A recent study from Tata Institute of Fundamental Research, Mumbai, India has revealed new details about how our cells clean up and recycle waste. This process, known as autophagy, is like a ...

(Wu et al., Science Advances, 2024) "An ideal therapeutic system for reducing the accumulation of neuronal alpha-synuclein aggregates, which has been a great challenge, would simultaneously ...

where both metabolic and autophagic dysfunctions are common. While this mechanism has so far only been shown in mice, further studies will investigate how autophagy regulates metabolism in both ...

Henan Key Laboratory of Environmental and Animal Product Safety, College of Animal Science and Technology, Henan University of Science and Technology, Luoyang 471000, Henan,China ...

In Alzheimer's disease, autophagy impairment was linked to the accumulation of beta-amyloid and tau proteins, further disrupting autophagic processes and creating a feedback loop. Similarly ...

However, the physiological significance of autophagic degradation of the nucleus remains unknown. Against this backdrop, a research team from Japan recently focused on an autophagy pathway that ...