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In Jewish communities, conversations about genetic risks often focus on BRCA mutations and breast cancer. But this American ...

Scientists have made a groundbreaking discovery in understanding the BRCA2 gene, offering new hope for cancer patients and those at high risk of developing the disease.

【导读】帕博西尼（Palbociclib）是一种CDK4/6抑制剂，在治疗HR+乳腺癌中发挥着至关重要的作用。然而，palbociclib的耐药性是一个值得进一步研究的重大问题。团队的研究发现，TMEM45A是palbociclib耐药性的潜在驱动因 ...

A global study revealed that young breast cancer patients with high risk BRCA mutations can have their risk of cancer recurrence reduced significantly by undergoing mastectomy and/or ovary removal, of ...

While genetic testing rates for advanced ovarian cancer have increased, gaps in physician understanding and confidence in interpreting results may limit optimal biomarker-driven treatment and patient ...

The 32-year-old teacher had two pregnancies since she found out she had inherited a gene that contributed to her colorectal cancer, which was diagnosed in August 2020. Her first pregnancy occurred ...

Genetics significantly impact cancer risk, particularly in inherited mutations like BRCA1/BRCA2, which increase ...