The mechanism of action underlying ketamine’s rapid antidepressant effects in patients with depression, both suffering from major depressive disorder (MDD) and bipolar disorder (BD), including ...

Other drugs may have side effects that stimulate the immune system, through transient lymphodepletion, by the subversion of immunosuppressive mechanisms ... their mode of action (for example ...

This review summarizes the mechanisms of action and clinical activity of IMiDs ... and the proteasome inhibitor bortezomib. [1] IMiDs are structural and functional analogs of thalidomide that ...

Canonically, the metabolic depletion of tryptophan and/or the accumulation of kynurenine is the mechanism that defines how immunosuppressive IDO inhibits immune cell effector functions and/or ...

Copy number variants (CNVs) arise by homologous recombination (HR) between repeated sequences (recurrent CNVs) or by non-homologous recombination mechanisms that occur throughout the genome (non ...

But sometimes you don’t want that! Sometimes you just want to escape the increasingly insane world out there into an action movie. Netflix has made a few of their own, but the bulk of the best ...

Paris: Sanofi has announced that the National Medical Products Administration (NMPA) in China has approved Sarclisa, in combination with a standard-of-care regimen, bortezomib, lenalidomide, ...

“Patients with multiple myeloma need treatment options after first relapse that are efficacious, readily accessible and have novel mechanisms of action,” commented Hesham Abdullah, global head ...

Annex I Parties under the Convention must provide information in their national communications under the Kyoto Protocol to demonstrate that their use of the mechanisms is supplemental to domestic ...

There’s a reason that the most successful genre on the home market has been the same for over a generation now: People love action movies. They allow us to escape reality and enter a world where ...

If you love Action/Adventure and you're looking for your next family favorite, you're in the right place. We've compiled a top list of the latest and greatest Action/Adventure Movies. Give it a scroll ...

Sarclisa (isatuximab) has been approved in China for use in combination with the VRd regimen to treat newly diagnosed multiple myeloma patients w ...