Chromosome abnormality is the condition in a cell or organism where the number of chromosomes or the structure of any chromosome differs from the normal karyotype. When the variant genotype is not ...

Researchers' initial understanding of meiosis was based upon careful observations of chromosome behavior using light microscopes. Then, in the 1950s, electron microscopy provided scientists with a ...

In particular, balanced translocations and inversions can neither be identified by microarrays since they do not alter chromosome copy numbers, nor by short-read sequencing because of the ...

Rapid FISH studies using probes specific for the X (DX1) and Y (SRY) chromosomes can provide useful information ... A mosaic karyotype, for example 45X/46XY suggests gonadal dysgenesis. There is a ...