Furthermore, the Sphk1/2 or Sphk2 inhibitor promoted the activities of histone deacetylase (HDAC1) and inhibited the histone acetylation of the Krüppel-like factor 4 (KLF4) promoter regions, ...

Glucose-6-phosphate dehydrogenase (G6PD) is the only rate-limiting enzyme in the pentose phosphate pathway (PPP). Rapidly proliferating cells require metabolites from PPP to synthesize ribonucleotides ...

Therefore, it may be important to develop collagen blends with chitosan to create more suitable biomimetic microenvironments for cells. Chitosan, with a degree of deacetylation of about 80%, was ...

SCIENCE CHINA Life Sciences近日以开放获取（OA）形式在线发表发表国家生物医学分析中心南湖实验室的满江红研究员、李爱玲研究员，与中国人民解放军 ...

This is a useful study that seeks to address the role of the TET family of DNA demethylation enzymes in pancreatic beta cell senescence in the context of type 2 diabetes (T2DM). Although the concepts ...