Explore the role of the extracellular matrix (ECM) in prostate cancer progression and discover natural therapies, including ...

Decades of research have disclosed a plethora of alterations in protein glycosylation that decisively impact in all stages of disease and ultimately contribute to more aggressive cell phenotypes. The ...

Our work proved that processing trajectory could effectively obtain a more reliable and robust quantitative model compared with the step-by-step optimization method. The use of systematic tracking was ...

These diseases, also known as Hunter and Hurler syndrome, are lysosomal storage deficiencies characterized by the buildup of heparan sulfate (HS) and dermatan sulfate (DS) in cells. Over time ...

A recent study has uncovered the essential roles of two proteoglycans, biglycan and decorin, in maintaining bone mass, water retention, and bulk/in situ mechanical competence. Through the use of ...

Correspondence to Przemko Tylzanowski, Skeletal Biology and Engineering Research Centre, KU Leuven, Leuven, Flanders, Belgium; przemko{at}kuleuven.be Human genetic diseases can be classified as ...