Most DUBs are Cys proteases; a small group are metalloproteases. DUBs are classified into five families (ubiquitin C-terminal hydrolases (UCHs), ubiquitin-specific proteases (USPs), Ovarian tumour ...

Proteins bearing C-terminal amides (CTAPs), a chemical modification caused by oxidative stress, are rapidly cleared from cells, they report. This occurs through interactions with the protein FBXO31.

Like any Linux beginner, I felt a bit intimidated by the Linux Terminal when I first switched to Linux. However, as I began exploring and learning some basic terminal commands, things started to ...

DC-SIGN (CD209/CLEC4L) is a C-type lectin receptor (CLR) that serves as a reliable cell-surface marker of interleukin 4 (IL-4)-activated human macrophages [M(IL-4)], which historically represent the ...

Peripheral nerve injuries arising from trauma or disease can lead to sensory and motor deficits and neuropathic pain. Despite the purported ability of the peripheral nerve to self-repair, lifelong ...

The future site of Roberts Bank Terminal 2 in Delta, B.C. (Georgie Smyth/CBC) The federal government argued in court that the conservation groups fundamentally misconstrued how the project will be ...

Giamundo et al. present fundamental data with new insights into the role of Ezrin, a major membrane-actin linker that assembles signaling complexes, in the spatial regulation of EGF signaling ...