Copy number variants (CNVs) arise by homologous recombination (HR) between repeated sequences (recurrent CNVs) or by non-homologous recombination mechanisms that occur throughout the genome (non ...

The question of putative mechanisms of action continues to haunt psychopharmacology. Put simply, we know these drugs work, but we have very little idea how. We make guesses based on the ...

Discover the best gifts for chefs and home cooks. Find the expert-approved kitchen gifts including a Ninja Mega Blender, Our ...

This article will review the mechanisms of activation of alternative, classical, and lectin pathways, the formation of C3 and C5 convertases, the action of anaphylatoxins, and the ...

Jalapeños are one of the most popular peppers in the US for good reason. They’re fresh, tangy, spicy, and tasty in everything ...

The most commonly mutated ALS-linked genes are reviewed with an emphasis on disease-causing mechanisms. The cellular processes involved in ALS pathogenesis are discussed, with evidence implicating ...

Correspondence to: Dr G J Gores Mayo Clinic College of Medicine, 200 First St SW, Rochester, Minnesota 55905, USA; gores.gregorymayo.edu ...

The International Telecommunication Union (ITU) and the World Benchmarking Alliance (WBA) have collaborated on the joint “Greening Digital Companies: Monitoring Emissions and Climate Commitments 2024” ...

As an additional means of meeting these targets, the Kyoto Protocol introduced three market-based mechanisms, thereby creating what is now known as the carbon market. Stimulate sustainable development ...

ORF3a, an accessory protein of SARS-CoV-2, mediates the transmembrane transport of water, leading to lysosome swelling. This function could, in principle, result in lysosome inactivation, a ...

Hereditary haemorrhagic telangiectasia (HHT, Rendu-Osler-Weber syndrome) exemplifies an important group of diseases which have catalysed advances in the understanding of fundamental pathophysiological ...