Small protein plays big role in chronic HIV infection
The study shows that intact HIV and its viral envelope protein gp120 each cause macrophages, a type of white blood cell, to ...
Medscape6d
Role of CXCR4 in HIV Infection and its Potential as a Therapeutic Target
Determinants of HIV cell tropism & chemokine receptor usage The V3 loop of HIV-1 gp120 is a primary determinant of cell tropism and chemokine receptor usage, whereas the V1/V2 region is involved ...
Nature9y
Bioinformatics prediction of HIV coreceptor usage
Preventing HIV cell entry There is no cure for AIDS ... viral strains carrying different maraviroc resistance–conferring mutations within gp120 have been observed both in cell culture ...
The Scientist9d
Opinion: Progress toward an HIV/AIDS vaccine
This vaccine used a recombinant canarypox vaccine to prime immune responses plus protein subunits of the HIV surface protein (termed gp120) to boost immune responses. Further analysis of the data ...
Nature4y
Recombinant HIV-1 Envelope Protein for Vaccine Use - Licensing and Collaboration Opportunity
Researchers at the Vaccine Research Center (“VRC”) have determined the three-dimensional structure of the HIV-1 Envelope trimeric ectodomain (“Env”), comprised of three gp120 and three ...