Abstract: This paper proposes a practical micropipette-image (2-D pixel and 3-D spatial coordination) calibration method indispensable to somatic cell microinjection, leveraging advancements in modern ...

Cells navigating in complex microenvironments frequently encounter narrow spaces that physically challenge migration.

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Waste clearance (WC) is an essential process for brain homeostasis, which is required for the proper and healthy functioning of all cerebrovascular and parenchymal brain cells. This review features ...

The open reading frame originated in mice. Transgenic mice overexpressing SMILE were generated on a C57BL/6 background by transgene microinjection and maintained at Macrogen Inc. (South Korea). SMILE ...

Intracellular kinases play a ubiquitous role in signaling pathways within cells. Receptor tyrosine kinases function at the beginning of a number of signal transduction cascades, whereas ...

Microinjection with genes encoding mutant but not wild-type SOD1 has also been found to provoke aggregate formation selectively in motor neurons, but not sensory or hippocampal neurons, and this ...

Successful year 12 applicants have the opportunity to participate in laboratory-based work experience and will be given an extended taste of the research environment within the School of Medicine.