Researchers at the University of Liège (Belgium) have uncovered a previously unknown mechanism that regulates the immune ...

T lymphocyte activation is a pivotal step of the adaptive immune response. It requires the recognition by T-cell receptors (TCR) of peptides presented in the context of major histocompatibility ...

In a mid-stage study, the candidate itolizumab achieved 23.3% clinical remission rate at 12 weeks, numerically better than ...

This review focus on updating and integrating findings on T lymphocyte signaling generated using global phosphoproteomics approaches, drawing attention on the biological relevance of the obtained data ...

Thus low concentrations of lymphocytes, suppressed natural immunity, suppressed lymphocyte proliferation, and suppressed levels of secretory IgA in saliva are found simultaneously with high levels of ...

Atypical lymphocytes that survive genetic damage ... Separation of atypical lymphoid proliferation from reactive hyperplasia and malignant lymphomas is shown in Figure 6. However, it should ...

Lymphocytes are white blood cells that have important immune functions. The main populations of lymphocytes are B cells, T cells and natural killer (NK) cells. They are typically (although not ...

Findings indicate that altering glucose metabolism in T cells boosts their therapeutic potential against melanoma, paving the way for improved immunotherapies.

Unlike other cells, activated lymphocytes expand their pyrimidine pool by approximately eightfold during proliferation; purine pools are increased only twofold. To meet this demand, lymphocytes must ...

Previous work on lymphocytes, Coller says, suggested that quiescence is associated with a “sleepy metabolic state” during which cells take up less glucose and excrete fewer waste products, such as ...

Cells navigating in complex microenvironments frequently encounter narrow spaces that physically challenge migration.