All lymph node biopsy samples were stained for CD19 (pan B-cell marker), CD20 (pan B-cell marker), CD138 (plasma cells), CD23 (follicular dendritic cells (FDCs)), PD-1 (follicular T helper cells, TFH) ...

In accordance with the marker genes (Figure S6D), the cells were classified into clusters 1–9 corresponding to proximal convoluted tubule cells, proximal tubule cells, glomerular parietal endothelial ...

While NOTCH guides thymus progenitors toward T cell fate, the absence or disruption of NOTCH signaling renders the thymus microenvironment permissive to other cell fates. Following T cell commitment, ...

15 Lymphoma cells from a pleural effusion in a pediatric patient with T-cell lymphoblastic disease ... surface CD3 and TCRαβ (Figure 1). Markers associated to B (CD19), NK (CD16/56) or ...

A personalized neoantigen cancer vaccine generated strong immune responses in renal cell carcinoma patients, leading to ...

In proliferating cells the tetramer:dimer ratio of M2-PK ... In combination with established tumor markers, EDTA-plasma Tumor M2-PK is a useful tool in diagnosis and/or surveillance of ...

Feb. 4, 2025 — Research has shown that a potential new targeted therapy for childhood brain cancer is effective in infiltrating and killing tumor cells in preclinical models tested in mice.

Jan. 30, 2025 — A research group has developed new advanced light-controlled tools that enable precise control of proteins in real time in living cells. This groundbreaking research opens doors ...

Thus, there is an urgent need for advanced therapies for patients suffering from severe and refractory autoimmune diseases, and researchers have considered cell therapy as potentially curative ...

We examined in detail the distribution of the full range of cell lineages within the human stomach. Design We determined the distribution of gastric gland cell lineages with specific ...

The management of Leishmania donova ni (LD), responsible for fatal visceral leishmaniasis (VL), faces increasing challenges due to rising drug-unresponsiveness, leading to increasing treatment ...