Pancreatic cancer is a challenge due to its poor prognosis and high mortality rate, highlighting the need for new therapeutic approaches. Previous findings have shown that AUS-001 inhibits β-tubulin ...

Strands of tubulin, a protein in the cell’s skeleton, photographed using a high-resolution microscopy Credit: NIH Image Gallery – CC BY-NC 2.0 via Flickr. A team of researchers that included ...

Here, we investigate how Elongator controls microtubule dynamics. Elongator binds both to the tip of microtubules and to free GTP-tubulin heterodimers using two different subcomplexes, Elp123 and ...