We performed fluorescence-based assays to analyze the concentration of cell free DNA and the activity of neutrophil elastase. The presence of citrullinated histone H3, as well as neutrophil elastase- ...

For instance, patients with RA develop autoantibodies against citrullinated proteins. 31 Citrullination is a post-translational modification of arginine that is catalyzed by peptidylarginine ...

Rheumatoid arthritis (RA) is an autoimmune disorder characterized by inflammation and bone erosion. The exact mechanism of RA is still unknown, but various immune cytokines, signaling pathways and ...

Correspondence to Professor Caifeng Li, Department of Rheumatology, Beijing Children's Hospital, Capital Medical University, National Centre for Children’s Health, Beijing, 100045, China; ...