Correspondence to Dr H U Scherer, Department of Rheumatology, Leiden University Medical Centre, P.O. Box 9600 Leiden 2300 RC, The Netherlands; h.u.scherer{at}lumc.nl Objective To determine whether ...

In the latter case differential diagnosis with other autoimmune diseases like rheumatoid arthritis (RA) is a challenge. In these situations, specific antibodies may be useful for making a correct ...

We performed fluorescence-based assays to analyze the concentration of cell free DNA and the activity of neutrophil elastase. The presence of citrullinated histone H3, as well as neutrophil elastase- ...

For instance, patients with RA develop autoantibodies against citrullinated proteins. 31 Citrullination is a post-translational modification of arginine that is catalyzed by peptidylarginine ...

Fibromyalgia and rheumatoid arthritis can cause similar symptoms like pain, reduced mobility in muscles, and exhaustion. The symptoms may be difficult to distinguish if a person has both conditions.

A significant percentage of patients with Lyme arthritis and other Lyme disease manifestations were positive for anti-RA33 antibodies.

Rheumatoid arthritis (RA) is an autoimmune disorder characterized by inflammation and bone erosion. The exact mechanism of RA is still unknown, but various immune cytokines, signaling pathways and ...

“The evidence behind the EULAR recommendation is obtained from studies in subgroups of patients using biological DMARDs or in subgroups of patients positive for anti-citrullinated protein ...