Production of IFN-γ, TNF-α and granzyme B was measured using flow cytometry. The target cells WM9, WiDr, HT29 and HAP1, were plated one day prior to the coculture with γδ T cells at a density of ...

As noted above, stellate cell activation is the central event in hepatic fibrosis. Activation consists of 2 major phases: (1) initiation (also called apreinflammatory stage) and (2) perpetuation ...

Objective Polymorphisms in the antifungal signalling molecule CARD9 are associated with ankylosing spondylitis (AS). Here, we investigated the cellular mechanism by which CARD9 controls pathogenic ...

5 KU Leuven—University of Leuven, Translational Research in Gastrointestinal Diseases (TARGID), Laboratory of Digestion and Absorption, Leuven, Belgium Correspondence to Professor Jeroen Raes, ...

Objectives The significance of neutrophilic inflammation in obstructive airway disease remains controversial. Recent studies have demonstrated presence of an active neutrophil population in systemic ...