A release of these groups, with subsequent recovery of enzyme activity, can be obtained in vitro by thiolic substances such as cystein or glutathione, which combine with the metallic ions.

In recent years, several important advances have been made in our understanding of the pathways that lead to cell dysfunction and death in Parkinson's disease (PD) and Huntington's disease (HD).

All caspases--aspartate-specific cystein proteases that mediate apoptosis and proinflammatory cytokine production--share structural similarities: a prodomain, a large subunit, and a small subunit.

Institute of Chemistry, Food Chemistry, Martin Luther University Halle-Wittenberg, Kurt-Mothes-Str. 2, 06120 Halle (Saale), Germany ...

The KRAS protein, a product of the KRAS gene (V-ki-ras2 Kirsten rat sarcoma viral oncogene homolog), functions as a small GTPase that alternates between an active GTP-bound state (KRAS(ON)) and an ...

Researchers at Mass General Brigham found that diets high in processed meats, including bacon, hot dogs, and sausage, were associated with a 13 percent higher risk of dementia in participants followed ...