Accumulating evidence reveals that adipose tissue is an immunologically active organ that exerts multiple impacts on the regulation of systemic energy metabolism. Adipose tissue immunity is modulated ...

1 Department of Cellular Biology, Physiology and Immunology, Autonomous University of Barcelona, Barcelona, Spain 2 Department of Microbiology & Immunology, Albert Einstein College of Medicine, New ...

The NCLs (neuronal ceroid lipofuscinosis) are pediatric neurodegenerative disorders. The nine clinical variants are caused by mutations in different genes (CLN1–CLN9). Six of the genes are ...

Department of Chemical Engineering, Northeastern University, Boston, Massachusetts 02115, United States ...

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induces apoptosis in various tumor cells in vitro, but its physiological role in tumor surveillance remains unknown. Here, we report ...

KD can occur in older children and adults, when the course of the disease can vary greatly. It is known that KD is caused by a deficiency of galactosylceramidase (GALC), an enzyme that breaks down ...

Department of Pharmaceutical Biosciences, Spatial Mass Spectrometry, Science for Life Laboratory, Uppsala University, SE-75124 Uppsala ,Sweden ...