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《自然免疫学》:免疫调节剂短形式的抗癌潜力
在《自然免疫学》杂志上发表的一项研究中,中国科学院上海免疫与感染研究所的孟广勋教授团队和上海交通大学医学院新华医院的刘辰莹教授团队揭示了一种新的机制,即肿瘤细胞中caspase-3切割产生的一种短形式的IL-18,激活自然杀伤细胞(NK)抑制肿瘤生长,为新的治疗提供了机会。
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