Objectives Systematic reviews and meta-analyses are the foundation of modern evidence-based medicine and their use is becoming more prolific than randomised trials. However, systematic reviews are ...

As a heart surgeon, you regularly perform aortic valve replacement, using a median sternotomy technique. However, you are aware that less-invasive options are available, and you wonder whether these ...

Correspondence to Dr Igho J Onakpoya, Nuffield Department of Primary Care Health Sciences, University of Oxford, Centre for Evidence-Based Medicine, Oxford OX2 6GG ...

Objective To estimate associations between trivalent influenza vaccination and COVID-19 mortality as well as severe clinical outcomes among hospitalised patients. Design Retrospective observational ...

2 Center for Evidence-based Medicine & Health Outcome Research, University of South Florida & H Lee Moffitt Cancer Center & Research Institute, Tampa, Florida, USA ...

Objectives Bronchiolitis is the commonest reason for hospital admission in infants in the first year of life. 1 Bronchiolitis, a viral chest infection, is a clinical diagnosis with no effective ...

Introduction There is growing interest in applying shared decision making approaches to support informed consent, a vital but challenging aspect of conducting clinical research. We systematically ...

1 Kuopio Research Centre of Geriatric Care and Unit of Clinical Pharmacology and Geriatric Pharmacotherapy, School of Pharmacy, University of Eastern Finland, kuopio Campus, Yliopistonranta 1, P.O.

4 Institute of Medical Biometry and Statistics (IMBI), Medical Center – University of Freiburg, Faculty of Medicine, Freiburg, Germany 5 Eye Center, Medical Center, Faculty of Medicine, University of ...

Correspondence to Dr Preeti Malik, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; pmalik.ma{at}gmail.com Objective To evaluate association between biomarkers and outcomes in ...

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Objectives Access to assisted reproductive technologies (ART) for those seeking treatment is dependent on their ability to afford such treatments. A combination of out-of-pocket payment, public ...