For each virus we expressed a small panel of recombinant variants of the membrane fusion protein and screened for expression level, product homogeneity, and the presence of the expected trimeric ...

How cells respond to mitochondrial DNA (mtDNA) damage is not fully understood. This study uncovers a mechanism of mtDNA ...

To adapt to constantly changing environmental conditions, plants have evolved sophisticated tolerance mechanisms to integrate various stress signals and to coordinate plant growth and development. It ...

You have full access to this article via your institution. Figure 2: Differential interaction of Apo2L trail versions with hepatocytes.

Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai 980-8578, Japan ...

This useful study introduces the peptidisc-TPP approach as a promising solution to challenges in membrane proteomics, enabling thermal proteome profiling in a detergent-free system. While the concept ...

"Obesity is gradually eroding human health," and the global prevalence of obesity (BMI > 30) is predicted to reach 25 % by 2035, affecting nearly 1.9 billion people. The demand for medications to ...

2 Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology RAS, Moscow, Russian Federation Objectives Neutralisation of tumour necrosis ...

Department of Engineering Physics, McMaster University, 1280 Main Street West, L8S 4L8 Hamilton, Ontario, Canada School of Biomedical Engineering, McMaster University, 1280 Main Street West, L8S 4L8 ...