However, mechanistic studies to support the conclusion that mitochondrial function is increased in the tumours remain incomplete and would benefit from experiments that would directly interrogate ...

The Inflation Reduction Act (IRA), passed in 2022, made changes to the way drugs are covered and reimbursed in Medicare.

CYP is an alkylating prodrug with antineoplastic and immunosuppressive properties. CYP is converted in the liver into two active metabolites, phosphoramide mustard and aldophosphamide, which ...

The dominant rationale to generate new (and to assess old) anticancer chemotherapeutic agents is to determine their cell-autonomous effects — that is, their capacity to reduce the growth ...

Combination therapies provide a synergistic effect and reduce drug resistance for the treatment of cancer. Cabozantinib possesses antineoplastic activity in mouse models of HCC by restraining the ...