2013). The autophagic process involves the formation of autophagosomes which are double membrane vesicles. Autophagosomes engulf portions of cytoplasm together with proteins, whole organelles or ...

A recent study from Tata Institute of Fundamental Research, Mumbai, India has revealed new details about how our cells clean up and recycle waste. This process, known as autophagy, is like a ...

This study presents a valuable finding on the alterations in the autophagic-lysosomal pathway in a Huntington's disease model. The evidence supporting the claims of the authors is solid. However, the ...

A recent study from Tata Institute of Fundamental Research, Mumbai, India has revealed new details about how our cells clean up and recycle waste.

Department of Chemical Sciences, Tata Institute of Fundamental Research, Mumbai 400005, India ...

where both metabolic and autophagic dysfunctions are common. While this mechanism has so far only been shown in mice, further studies will investigate how autophagy regulates metabolism in both ...

Henan Key Laboratory of Environmental and Animal Product Safety, College of Animal Science and Technology, Henan University of Science and Technology, Luoyang 471000, Henan,China ...

(Wu et al., Science Advances, 2024) "An ideal therapeutic system for reducing the accumulation of neuronal alpha-synuclein aggregates, which has been a great challenge, would simultaneously ...

Genotoxic stressors, including oxidative stress, inflammation, and environmental factors are closely intertwined processes that significantly contribute to ...