Developed for the treatment of fibrosis in the liver, lungs and kidneys, lixudebart targets the claudin-1 (CLDN1) epitope found in fibrotic tissue. Following Phase I trials, the therapy was ...
Claudin-1 (CLDN1) is a protein usually found nestled between epithelial cells — which cover internal and external body surfaces — helping to bind them. “It works like a zipper to keep two ...