Hypoxia-driven gene and protein changes enhance epithelial-to-mesenchymal transition, remodel the extracellular matrix, drive drug resistance, support cancer stem cells and aid evasion from immune ...

Hypoxia can drive the metastatic phenotype secondary to genetic instability, increased angiogenesis, decreased apoptosis and upregulation of a number of genes involved in the metastatic cascade ...

Altitude Training Exercise Physiology Fitness Testing Soccer In 2007, Wilber1 presented the main altitude/hypoxic training methods used by elite athletes: ‘live high—train high’ (LHTH) and ‘live ...