Oxidative stress plays a critical role in the pathogenesis of upper and lower respiratory tract diseases, such as chronic rhinosinusitis with nasal polyps (CRSwNP), allergic rhinitis (AR), and asthma ...

Elevated liver enzymes can occur for many reasons. Most often, elevated liver enzymes are temporary and resolve on their own without treatment. Occasionally, elevated liver enzymes require additional ...

The team evaluated more than 4,000 clones before identifying an enzyme S N Ar1.3 that contains six mutations and is 160-fold more active than the parent enzyme.

Temperature affects enzyme-catalysed reactions by influencing the rate at which they occur. For a reaction to occur between an enzyme and substrate the two molecules need to collide. At lower ...

The engineered enzymes had similar gene-editing efficiency and reduced immune responses compared to standard nucleases in mice. Appearing today in Nature Communications, the findings could help ...

All COX2 inhibitors undergo oxidative drug metabolism by cytochrome P450 (CYP) enzymes. Celecoxib has ... extensive records of papers on cyclo-oxygenase-2 and cyclo-oxygenase-2 inhibitors dating ...

Parasites also express a divergent heme oxygenase (HO)-like protein (PfHO ... which selectively associates with the apicoplast genome and enzymes involved in nucleic acid metabolism and gene ...