Here, we investigate how Elongator controls microtubule dynamics. Elongator binds both to the tip of microtubules and to free GTP-tubulin heterodimers using two different subcomplexes, Elp123 and ...
A phase 1/2 study evaluating the safety and efficacy of autologous TAC T cells in subjects with claudin 18.2+ advanced solid tumors. This is an ASCO Meeting Abstract from the 2025 ASCO ...
Pancreatic cancer is a challenge due to its poor prognosis and high mortality rate, highlighting the need for new therapeutic approaches. Previous findings have shown that AUS-001 inhibits β-tubulin ...
Innovative targeted oncology company built on next-generation ADCs and a novel discovery engine Connect with the Company on ...
A team of researchers designed AI model capable of generating new proteins, trained on a simulation of 500 million years of evolution.
William Wood, an analyst from B.Riley Financial, maintained the Buy rating on Veru (VERU – Research Report). The associated price target ...
You have full access to this article via your institution. In summary, QuickPALM in conjunction with the acquisition control features mentioned above (Supplementary Discussion) provides a complete ...
The PIF/Harbinger-derived ADF-IL protein recruits KAT2B to drive its nuclear translocation and local chromatin acetylation, ...
CAMBRIDGE, MA—Mersana Therapeutics, Inc. (NASDAQ:MRSN) recently reported that Ashish Mandelia, the company's Vice President and Chief Accounting Officer, executed a sale of common stock. According to ...
This study presents TBorNotTB, a CDSS designed to improve TB evaluation and streamline isolation decisions, reducing labor ...
Telotristat ethyl to promote weight stability in patients with advanced pancreatic cancer. This is an ASCO Meeting Abstract from the 2025 ASCO Gastrointestinal Cancers Symposium. This abstract does ...
Mersana's management has targeted Triple-Negative Breast Cancer (TNBC) patients with their initial dose-expansion, addressing an area of opportunity due to XMT-1660's unique anti-tubulin payload.