lung cancer research has classically focused on molecular drivers of disease. One such pathway, the hypoxic response pathway, is activated by reduced local oxygen concentrations at the tumor site.

A new approach that used CRISPR to engineer adipocytes and implant them in mice models of cancer reduced cancer progression.

One of the most significant challenges in cancer treatment is the development of drug resistance by cancer cells, which often leads to treatment failure. When we say the body "resists" cancer ...

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However, for both TACE and TAE the resulting hypoxia will be a potent stimulator of angiogenesis, so that embolization might inadvertently promote tumor growth by rending the tumor hypoxic.

Jan. 28, 2025 — A new study shows that asymptomatic brain metastasis is more common in stage 4 breast cancer patients than previously believed. The study suggests that doctors may need to ...

Macrophages exist in most tissues of the body, where they perform various functions at the same time equilibrating with other cells to maintain immune responses in numerous diseases including cancer.

Understanding how adenosine affects our immune system is crucial for developing effective treatments for diseases like cancer. Elevated adenosine levels, primarily produced in hypoxic tumor conditions ...

More than 67,000 Americans will be diagnosed with pancreatic cancer this year. Learn more about the disease and how PanCAN can help.

But despite its primary role to prevent pregnancy, the contraceptive pill (or 'the Pill') could also help reduce the risk of ovarian cancer, according to new ... Inhibitor Drugs to Treat ...

retriever generates disease-specific transcriptional drug response signatures by merging transcriptional signatures over time, concentration, and cell-type. These signatures can then be matched to ...