Elevated uric acid in children with severe malaria is associated with increased risks of death and long-term cognitive ...

Objectives In the past decade, China has been characterised by large-scale urbanisation as well as rapid economic growth. The aim of this study was to further investigate the prevalence of ...

This case–control study was designed to analyse whether hURAT1 might also be a candidate gene for hyperuricaemia or hypouricaemia. Setting We recruited 68 healthy volunteers and divided them into two ...

除了饮食，情绪压力也是高尿酸的重要诱因。日本一项研究发现，工作压力和高脂肪饮食习惯与高尿酸血症密切相关。同济大学附属第十人民医院的研究也表明，高压力人群的痛风发作频率显著高于低压力人群。

1 Division of Rheumatology, La Paz University Hospital, Madrid, Spain 2 Division of Internal Medicine, La Paz University Hospital, Madrid, Spain 3 Division of Clinical Biochemistry, La Paz University ...

OBJECTIVES To study the efficacy of allopurinol and benzbromarone to reduce serum urate concentrations in patients with primary chronic gout. METHODS Prospective, parallel, open study of 86 ...

Diabetic nephropathy (DN) is the main cause of end-stage renal disease (ESRD), which is characterized by a series of abnormal changes such as glomerulosclerosis, podocyte loss, renal tubular atrophy ...

Objective Verinurad (RDEA3170) is a high-affinity, selective URAT1 inhibitor in development for treating gout and asymptomatic hyperuricaemia. This study evaluated the pharmacodynamics, ...

Introduction: Achieving a goal of serum urate levels in patients with gout is an important way to prevent gout and its complications while it remains difficult with a low targeting rate worldwidely.

7 Department of Neurology, Queen Elizabeth Hospital, Edgbaston, Birmingham, UK 8 Department of Neurology, King's College Hospital and King's College School of Medicine, London, UK Correspondence to Dr ...

Objectives To evaluate the sensitivity to change of ultrasound structural gout lesions, as defined by the Outcome Measures in Rheumatology (OMERACT) ultrasound group, in patients with gout during ...