As night falls over Australia's forests, grasslands and backyards, the hidden world of nocturnal insects stirs to life. In ...

Imaging live cells with fluorescent proteins has long been a crucial technique for understanding cellular behavior. While bioluminescent proteins offer several advantages over fluorescent proteins, ...

Dec. 6, 2024 — A newly developed luciferase-based reporter can detect problems in protein translocation and disulfide bond formation in the endoplasmic reticulum (ER). Inspired by natural ...

Furthermore, we identified the effect of SMAD4 on metabolic reprogramming by metabolomics and glucose metabolism gene expression analyses. Dual luciferase reporter assays and chromatin ...

Imaging live cells with fluorescent proteins has long been a crucial technique for understanding cellular behavior. While ...

Researchers have expanded the colour palette of bioluminescent protein to 20 distinct colours, enabling advanced simultaneous multicolour imaging.

This database includes grant commitments made by the Gates Foundation and previous foundations of the Gates family (William H. Gates Foundation, Gates Library Foundation, and Gates Learning Foundation ...

尽管如此，本研究为 65 岁以上老年人接种三种基于蛋白的含 XBB 疫苗后的中和抗体反应提供了重要证据，为优化老年人群疫苗接种策略、增强对新兴 SARS-CoV-2 变体的中和免疫力提供了关键信息。未来需进一步研究不同给药途径疫苗诱导的免疫特征、年龄对加强免疫后免疫力持久性的影响以及疫苗对新变体的效力等问题，以更好地应对新冠疫情，保障老年人群健康。

This important study provides solid evidence to support the anti-tumor potential of citalopram, originally an anti-depression drug, in hepatocellular carcinoma (HCC). In addition to their previous ...

Here we explore peptide inhibitors of Cdc20, a substrate-recognition subunit and activator of the E3 ubiquitin ligase the anaphase promoting complex/cyclosome (APC/C) that is essential in mitosis and ...