The proteasome is a large protein complex in the cytoplasm of eukaryotic and archaeal cells responsible for proteolysis of proteins that have one or more poly-ubiquitin post-translational ...

1Division of Neuro-Oncology, Brain Tumor Center, Keck School of Medicine of University of Southern California, Los Angeles, California.

In their manuscript, authors Isotani et al used in vivo and ex vivo models to show that nicotine could promote stemness and tumorigenicity in murine model. The authors further provided data supporting ...