To download a certificate of analysis for MDA-MB-231 (HTB-26), enter the lot number exactly as it appears on your product label or packing slip.

The MDA-MB-231 cell line (isolated at M D Anderson from a pleural effusion of a patient with invasive ductal carcinoma) is commonly used to model late-stage breast cancer. This cell line is ER, PR, and E-cadherin negative and expresses mutated p53.

MDA-MB-231 cells, the triple-negative breast cancer (TNBC) cell line, display representative epithelial to mesenchymal transition (EMT) associated with BC metastasis. However, the characterization of MDA-MB-231 spheroids has been largely unknown at present, which requires further attention.

2024年12月19日 · Gene expression profiling and pathway analysis data in MCF-7 and MDA-MB-231 human breast cancer cell lines treated with dioscin. Data Brief 8:272-279(2016) PubMed= 27377824 ; DOI= 10.1038/sdata.2016.52 ; PMCID= PMC4932877

2024年12月9日 · MDA-MB-231 is a metastatic triple-negative breast cancer (TNBC) cell line widely used as a model in breast cancer research. TNBC is an aggressive subtype lacking estrogen, progesterone, and HER2 receptors, making it challenging to treat.

MDA-MB-231 Cell Line; MDA-MB-231 was isolated from pleural effusions of a Caucasian breast cancer patient. Bulk and Prepack available at Sigmaaldrich.com.

The MDA-MB-231 cell line is used to create the CDX (Cell Line Derived Xenograft) MDA-MB-231 xenograft mouse model. The MDA-MB-231 xenograft model is HER2 negative, CK18 and EGFR positive and exhibits tumor growth inhibition from herceptin, lapatinib and trastuzumab.

In vivo selection of the MDA-MB-231br/eGFP cancer cell line to obtain a clinically relevant rat model for triple negative breast cancer brain metastasis.

To explore the relationship between NKD1 and the biological behavior of breast cancer cells, we upregulation NKD1 function by using gene transfection technology in the MDA-MB-231 cell line which has low endogenous NKD1 expression. Cancer metastasis is a major cause of morbidity in cancer patients.

MDA-MB-231 TGL is a parental breast adenocarcinoma cell line and a triple negative breast cancer (TNBC) cell line. It is also known as MDA231-TGL. This cell line is part of a panel of human breast cancer cell lines selected to metastasize to specific organs.