Pergolide, sold under the brand name Permax and Prascend (veterinary) among others, is an ergoline -based dopamine receptor agonist used in some countries for the treatment of Parkinson's disease.

2023年9月28日 · Easy-to-read patient leaflet for Pergolide. Includes indications, proper use, special instructions, precautions, and possible side effects.

Pergolide is a long-acting dopamine agonist approved in 1982 for the treatment of Parkinson’s Disease. It is an ergot derivative that acts on the dopamine D2 and D3, alpha2- and alpha1-adrenergic, and 5-hydroxytryptamine (5-HT) receptors.

2024年3月25日 · Pergolide package insert / prescribing information for healthcare professionals. Includes: indications, dosage, adverse reactions and pharmacology.

2022年8月16日 · Permax (pergolide mesylate) is indicated as adjunctive treatment to levodopa/carbidopa in the management of the signs and symptoms of Parkinson†s disease.

2023年5月6日 · Learn about the side effects of pergolide, from common to rare, for consumers and healthcare professionals.

Pharmacodynamic properties: Pergolide is a semisynthetic ergoline dopamine agonist used in the treatment of Parkinson's disease. It has potent activity at presynaptic dopamine D2 receptors but is also active at postsynaptic D2 and dopamine D1 receptors.

USES: This medication is used to treat Parkinson's disease. It can improve your ability to move and decrease shakiness (tremor), stiffness, slowed movement, and unsteadiness.

2010年3月15日 · Pergolide is a long-acting dopamine agonist approved in 1982 for the treatment of Parkinson’s Disease. It is an ergot derivative that acts on the dopamine D2 and D3, alpha2- and alpha1-adrenergic, and 5-hydroxytryptamine (5-HT) receptors.

Pergolide is a potent dopamine receptor agonist. Pergolide is 10 to 1000 times more potent than bromocriptine on a milligram per milligram basis in various in vitro and in vivo test systems.