Cytoprotection is defined as an ability of pharmacologic agents, originally PGs, to prevent gastric and intestinal mucosal injury produced by a variety of ulcerogenic agents (eg, aspirin, indomethacin, bile acids) and by necrotizing agents (eg, boiling water, absolute alcohol, 0.6 mol/L HCl, 0.2 mol/L NaOH).

Cytoprotection is a process by which chemical compounds provide protection to cells against harmful agents. [1] A gastric cytoprotectant is any medication that combats ulcers not by reducing gastric acid but by increasing mucosal protection. [2] .

The term cytoprotection is used here to differentiate between the indirect protection afforded by detoxification of ROS initiated by xenobiotics and the direct detoxification of xenobiotic reactive metabolites discussed earlier under detoxification.

细胞保护作用（cytoprotection）是1989年公布的生理学名词。 1989年，经全国科学技术名词审定委员会审定发布。 《生理学名词》第一版。 [1] 细胞保护作用（cytoprotection）是1989年公布的生理学名词。

Mucosal defense and protection, initially termed cytoprotection, was originally described as the ability of prostaglandins to prevent macroscopic evidence of gastric mucosal injury. This protective phenomenon is partially dependent on the antisecretory activity of prostaglandins, and is dose- and route-dependent.

2012年8月16日 · Increasing evidence indicates that cytoprotection via preservation of mitochondrial function is a promising therapeutic strategy to limit the severity of the diseases and their progression. In this special issue, we have invited reviews that discuss the interest and the modalities of cytoprotection in diverse conditions or experimental settings.

Examples of cytoprotective agents include dexrazoxane (ICRF-187), protecting against doxorubicin cardiotoxicity, and amifostine protecting against the myelosuppression of platinum and alkylating agents.

Cytoprotection can be defined as the ability to protect cells against wide variety of damaging agents. A series of recent studies indicate that many substances participate in this process. It has been proved that different mechanisms as inhibition …

2016年5月24日 · We review a class of cutting-edge approaches for cytoprotection of cells exposed to assaults such as sustained deformations, chemotherapy, radiotherapy, or ischemia. These approaches will enhance cell survival by mechanically protecting the structure and dynamics of the actin cytoskeleton (CSK).

1999年4月1日 · Historically, the concept of cytoprotection came into being with the use of leucovorin (LV) or citrovorum factor (CF) as a cytoprotectant with methotrexate (MTX). Briefly, MTX blocks the enzyme dihydrofolate reductase, which is necessary for the synthesis of tetrahydrofolate and other forms of reduced folates.