2024年10月30日 · A germinoma is the most common germ cell tumor that forms in your brain. A type of cancer, it’s most commonly diagnosed in children, teens and young adults. Symptoms include fatigue, nausea and vomiting, vision changes and hormone-related problems.

Germinomas are rare tumors that primarily occur in children and adolescents. These tumors arise from germ cells, which normally become eggs or sperm after migrating to the ovaries or testes during fetal development. Germinomas occur when these germ cells fail to migrate to the proper location and continue dividing.

What is a germinoma? A germinoma is a type of germ cell tumor that is most often found in the brain. Typically, germ cells migrate to the reproductive organs (female ovaries or male testes) during fetal development.

Since 1994, MeSH has defined germinoma as "a malignant neoplasm of the germinal tissue of the gonads, mediastinum, or pineal region" [4] and within its scope included both dysgerminoma and seminoma. Collectively, these are the seminomatous or germinomatous tumors.

Germinoma, a rare type of germ cell tumour, primarily affects the central nervous system. These tumours can occur in the brain or spinal cord, disrupting normal function and posing significant health challenges.

We classify germ cell tumors of the brain into two main types: Germinomas: These are pure germ cell tumors. They respond well to treatment. Non-germinomatous tumors: These tumors secrete chemicals into the spinal fluid and bloodstream. They …

In this manuscript, we review the literature focusing on the epidemiology, histopathology with molecular biology, clinical presentation with emphasis on tumor location, diagnostic workup, and current treatment strategies with related clinical outcomes of intracranial germinomas.

2022年3月25日 · A germinoma is a rare form of cancer that is most often found in the brain of children between the ages of 10 and 19 years. The cancer originates in germs cells, which are actually sex cells that fail to leave the brain when the fetus is still in utero.

What Is Childhood Germinoma? A germinoma is a type of germ cell tumor commonly found in the brain. Germ cells typically migrate to the gonads during fetal development and become an egg in female ovaries or sperm in male testes.

A germ cell tumor may be either a pure germinoma, a non-germinomatous GCT tumor (NGGCT), or a mixed germ cell tumor. There is a subtype of germinoma that is referred to a secretory germinoma or germinoma with syncytiotrophoblastic features, or intermediate risk germinoma.