2017年4月28日 · Hyperosmotic can refer to solutions that have increased osmotic pressure, or a greater difference between solutes and solutions between a membrane. In other instances, hyperosmotic refers to a solution that has more solutes, or components of a solution, than a similar solution.

2022年6月16日 · Hyperosmotic (biology definition): (1) of, relating to, or characterized by an increased osmotic pressure (typically higher than the physiological level); (2) a condition in which the total amount of solutes (both permeable and impermeable) in a solution is greater than that of another solution.

Hyperosmotic stress is linked to many maladies, including acute and chronic, as well as local and systemic, inflammatory disorders. Hyperosmolarity triggers cell shrinkage, oxidative stress, protein carbonylation, mitochondrial depolarization, DNA damage, and cell cycle arrest, thus rendering cells susceptible to apoptosis.

Hyperosmotic stress results from an extracellular osmolyte or solute concentration in the serum (or medium) that is higher than physiological, and high in comparison to the intracellular environment. Hyperosmolality is classified as hypertonic or isotonic according to whether cell shrinkage occurs.

2023年2月1日 · Hyperosmotic stress triggers an evolutionally preserved, fundamental cellular response. A growing body of evidence has highlighted the role of extra-renal, interstitial hyperosmolality in maintaining local tissue immune homeostasis and potentially driving tissue inflammation in human diseases.

Having an osmolality greater than that of another fluid, ordinarily assumed to be plasma or extracellular fluid. 2. Relating to increased osmosis. Of a fluid having a concentration of solutes great than that of the normal extracellular fluid. Hypertonic, containing a higher concentration of salts or other dissolved materials than normal tissues.

Osmoadaptation allows cells to survive and function under potentially cytotoxic conditions. This review covers the pathological consequences of hyperosmotic stress in relation to disease and emphasizes the importance of considering hyperosmolarity in inflammation and …

Hyperosmotic refers to a solution with a higher osmotic pressure compared to another solution, while hypertonic refers to a solution with a higher concentration of solutes compared to another solution.

2012年8月1日 · Osmoadaptation allows cells to survive and function under potentially cytotoxic conditions. This review covers the pathological consequences of hyperosmotic stress in relation to disease and emphasizes the importance of considering hyperosmolarity in inflammation and disease progression.

2024年2月28日 · Hyperosmotic refers to a solution with a higher concentration of solutes compared to another, leading to a potential movement of water towards the hyperosmotic solution. Hypoosmotic solutions, conversely, have fewer solutes, potentially causing water to move away from these solutions.