Oophorectomy (/ ˌoʊ.əfəˈrɛktəmi /; from Greek ᾠοφόρος, ōophóros, 'egg-bearing' and ἐκτομή, ektomḗ, 'a cutting out of'), historically also called ovariotomy, is the surgical removal of an ovary or ovaries. [1] .

An ovariectomized rodent (OVX) is a female rat or mouse whose ovaries have been removed. Currently, there is no single animal model that precisely replicates the stages of osteoporosis in humans, [1] although there are some animals that are relatively close and can be used for comparative purposes. Both small and large animals are used ...

The meaning of OVARIECTOMIZE is to surgically remove an ovary from.

The ovariectomized (OVX) rat model is the approved preclinical model by the Food and Drug Administration (FDA) for studying how the decline in endogenous estrogen production by the ovaries at menopause leads to postmenopausal osteoporosis and how potential interventions can preserve bone metabolism in this state.

The ovariectomized rat model of osteoporosis mimics the estrogen deficiency-induced bone loss and shows clinical manifestations of postmenopausal osteoporosis (Jee and Yao, 2001; Kimmel, 2001).

As such, ovariectomy represents a simple method to remove the major source of production of estrogen and progesterone. Then either estrogen or progesterone may be added back to investigate which hormone or combination is needed to prove a …

2020年1月10日 · The aim of this study is to provide a 4-step guideline for inducing a rat model of osteoporosis by ovariectomy (OVX): (1) selection of the rat strain, (2) choosing the appropriate age of rats at the time of OVX, (3) selection of an appropriate surgical method and verification of OVX, and (4) evaluation of OVX-induced osteoporosis.

An oophorectomy is surgery to remove one or both of the ovaries. The ovaries are almond-shaped organs that sit on each side of the uterus in the pelvis. The ovaries contain eggs and produce hormones that control the menstrual cycle. When an oophorectomy (oh-of-uh-REK-tuh-me) involves removing both ovaries, it's called bilateral oophorectomy.

removal of one or both ovaries; done for tumors, severe infection, or certain other ovarian disorders. If this is done to a girl who has not yet reached puberty, it prevents the development of secondary sex characters.

2025年1月20日 · Ovariectomy is the procedure wherein either one or both the ovaries are removed from the reproductive system of a woman. The ovaries are two almond shaped organs present on two sides of the uterus and its function is to produce and release eggs.