The enzyme cholinesterase (EC 3.1.1.8, choline esterase; systematic name acylcholine acylhydrolase) catalyses the hydrolysis of choline-based esters: an acylcholine + H 2 O = choline + a carboxylate. Several of these serve as neurotransmitters. [1]

2018年12月13日 · Cholinesterase is an enzyme required for function in the nervous system and is responsible for breaking down acetylcholine (a neurotransmitter), so that it does not over-stimulate post-synaptic nerves, muscles, and exocrine glands. It can be affected by genetic factors and poisoning.

RBC cholinesterase, true cholinesterase, red cell cholinesterase, acetylcholinesterase, AChE, PCHE. What is this test? This test looks for signs of chemical poisoning in your blood. Cholinesterase is an enzyme that helps your nervous system work the way it should.

Cholinesterases (ChEs) are a ubiquitous group of enzymes that hydrolyze esters of choline. A well-known example is acetylcholinesterase (AChE, acetyl choline hydrolase, EC 3.1.1.7), the enzyme responsible for hydrolyzing the important neurotransmitter acetylcholine (ACh).

2023年4月29日 · Serum cholinesterase is a blood test that looks at levels of 2 substances that help the nervous system work properly. They are called acetylcholinesterase and pseudocholinesterase. Your nerves need these substances to send signals. Acetylcholinesterase is found in nerve tissue and red blood cells.

2023年7月17日 · This activity describes the indications, action, and contraindications for cholinesterase inhibitors in treating dementia disorders and other uses within other specialties.

Cholinesterases (ChEs) are a ubiquitous group of enzymes that hydrolyze esters of choline. A well-known example is acetylcholinesterase (AChE, acetylcholine hydrolase, EC 3.1.1.7), the enzyme responsible for hydrolyzing the important neurotransmitter acetylcholine (ACh).

Cholinesterase is a plasma enzyme, produced by the liver, which is capable of hydrolysing a variety of choline esters. Plasma activity falls with decreased protein synthesis in liver disease. Enzyme levels generally follow a path similar to that of plasma albumin.

Cholinesterases are fundamental players in the peripheral and central nervous systems. These serine hydrolases are presented by a two-membered family, namely acetylcholinesterase (AChE, E.C. 3.1.1.7) and butyrylcholinesterase (BChE, E.C. 3.1.1.8). Under physiological conditions, AChE terminates the action of acetylcholine at synapses.

Apparent high cholinesterase is a marker of a high risk of atherosclerotic cardiovascular disease. The cholinesterase level can be increased under several conditions, including fatty liver, diabetes, and obesity (1, 5).